Clinical Images: Rheumatoid nodules in synovium
نویسندگان
چکیده
منابع مشابه
The Synovium in Rheumatoid Arthritis
Rheumatoid arthritis (RA) is a chronic autoimmune disease targeting multiple joints. The synovium is the primary site of the inflammatory process, which if untreated leads to irreversible damage to the adjacent cartilage and bone. It is now well established that autoantibodies that are characteristic of RA, including rheumatoid factor (RF) and anti-citrulluninated protein antibodies (ACPA), are...
متن کاملA comparative phenotypical analysis of rheumatoid nodules and rheumatoid synovium with special reference to adhesion molecules and activation markers.
OBJECTIVES (1) To analyse the in situ expression of adhesion molecules in rheumatoid nodules. (2) To compare the endothelial expression of adhesion molecules in synovial tissue and subcutaneous nodules obtained from the same patients. (3) To compare the expression of adhesion molecules and activation markers on T cell lines from nodules and synovium. METHODS (1) Immunohistochemical analysis b...
متن کاملAutoimmune Responses in the Rheumatoid Synovium
Perspective R heumatoid arthritis (RA) is a chronic inflammatory disorder affecting joints, often with severe and disabling consequences. Although cells and intracellular signals characterizing inflamed tissue in RA are not qualitatively different from those found in other conditions, in about one third of patients with RA ectopic lymphoid structures can be found in affected tissue [1]. These s...
متن کاملSubcutaneous nodules in rheumatoid arthritis.
A 29 year old male with rheumatoid arthritis (RA) of 10 years duration presented with multiple subcutaneous nodules of one month duration while on methotrexate (7.5 mg once a week), salazopyrine (1000 mg/day) and methyl prednisolone (4 mg/day). The nodules involved tendons of metacarpophalangeal joints (Figure 1) and base of left great toe (Figure 2), were painless and did not interfere with hi...
متن کاملSubcutaneous Rheumatoid Nodules.
death to give reliable results. The postmortem interval as already defined established fixed limits for the interval and avoided possible overestimation of the amino acid concentration relative to time after death. Analysis of the results showed no evidence that a specific aminoacidopathy is implicated in the aetiology of cot death but has nevertheless improved our understanding of the biochemi...
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ژورنال
عنوان ژورنال: Arthritis & Rheumatism
سال: 2007
ISSN: 0004-3591,1529-0131
DOI: 10.1002/art.22695